Adherence of Haemophilus somnus to tumor necrosis factor-alpha-stimulated bovine endothelial cells in culture.

@article{Kwiecien1994AdherenceOH,
  title={Adherence of Haemophilus somnus to tumor necrosis factor-alpha-stimulated bovine endothelial cells in culture.},
  author={J M Kwiecien and Paul Brian Little and Michael A. Hayes},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={1994},
  volume={58 3},
  pages={211-9}
}
Vascular thrombosis and tissue infarction is a principal lesion in Haemophilus somnus septicemia known also as thrombotic meningoencephalitis. This study was undertaken to examine whether tumor necrosis factor-alpha (TNF-alpha) can influence the adherence of H. somnus to cultured bovine aortic endothelial cells (BAEC). Confluent BAEC were exposed to 0-100 nM of human recombinant TNF-alpha for 12-48 h. Suspensions of different strains of H. somnus (approximately 1.5-3 x 10(8) labelled with… CONTINUE READING
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