Adherence and Persistence with Methotrexate in Rheumatoid Arthritis: A Systematic Review.

Abstract

OBJECTIVE Medication adherence in patients with rheumatoid arthritis (RA) is typically suboptimal. Nonadherence has been associated with symptom worsening and increased disability. We systematically reviewed published clinical studies to evaluate methotrexate (MTX) adherence and persistence, factors associated with MTX adherence and persistence, and the… (More)

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@article{Curtis2016AdherenceAP, title={Adherence and Persistence with Methotrexate in Rheumatoid Arthritis: A Systematic Review.}, author={Jeffrey R. Curtis and Vivian Patricia Bykerk and Maher Aassi and Michael H. Schiff}, journal={The Journal of rheumatology}, year={2016}, volume={43 11}, pages={1997-2009} }