Adequate sedation with single-dose dexmedetomidine in patients undergoing transurethral resection of the prostate with spinal anaesthesia: a dose–response study by age group

@inproceedings{Kim2015AdequateSW,
  title={Adequate sedation with single-dose dexmedetomidine in patients undergoing transurethral resection of the prostate with spinal anaesthesia: a dose–response study by age group},
  author={Jeong Min Kim and Won Oak Kim and Hye-Bin Kim and Hae Keum Kil},
  booktitle={BMC anesthesiology},
  year={2015}
}
BACKGROUND Dexmedetomidine (DMT), a highly selective α2-adrenoceptor agonist, has been used safely as a sedative in patients under regional anesthesia. The purpose of this study was to determine the 50% effective dose (ED50) of single-dose DMT to induce adequate light sedation in elderly patients in comparison with younger patients undergoing transurethral resection of the prostate (TURP) with spinal anesthesia. METHODS Forty-two male patients were recruited. The young age group (Group Y… CONTINUE READING