Adenylosuccinate synthetase from maize. Purification, properties, and mechanism of inhibition by 5'-phosphohydantocidin.

@article{Walters1997AdenylosuccinateSF,
  title={Adenylosuccinate synthetase from maize. Purification, properties, and mechanism of inhibition by 5'-phosphohydantocidin.},
  author={Eric W. Walters and Song Fong Lee and Thierry Niderman and Paula Bernasconi and Mani V. Subramanian and Daniel L. Siehl},
  journal={Plant physiology},
  year={1997},
  volume={114 2},
  pages={549-55}
}
Adenylosuccinate synthetase (AdSS) is the site of action hydantocidin, a potent microbial phytotoxin. A kinetic analysis of the mode of inhibition of a plant adenylosuccinate synthetase by the active metabolite 5'-phosphohydantocidin (5'-PH) was the objective of the present study. AdSS was purified 5800-fold from maize (Zea mays), to our knowledge the first… CONTINUE READING