Adenylate kinases 1 and 2 are part of the accessory structures in the mouse sperm flagellum.

@article{Cao2006AdenylateK1,
  title={Adenylate kinases 1 and 2 are part of the accessory structures in the mouse sperm flagellum.},
  author={Wenlei Cao and Lisa A Haig-Ladewig and George L. Gerton and Stuart B. Moss},
  journal={Biology of reproduction},
  year={2006},
  volume={75 4},
  pages={492-500}
}
Proper sperm function depends on adequate ATP levels. In the mammalian flagellum, ATP is generated in the midpiece by oxidative respiration and in the principal piece by glycolysis. In locations where ATP is rapidly utilized or produced, adenylate kinases (AKs) maintain a constant adenylate energy charge by interconverting stoichiometric amounts of ATP and AMP with two ADP molecules. We previously identified adenylate kinase 1 and 2 (AK1 and AK2) by mass spectrometry as part of a mouse SDS… CONTINUE READING