Adenyl cyclase activity and cyclic 3',5'-AMP content of ejaculated monkey spermatozoa.

  title={Adenyl cyclase activity and cyclic 3',5'-AMP content of ejaculated monkey spermatozoa.},
  author={E. Casillas and D. Hoskins},
  journal={Archives of biochemistry and biophysics},
  volume={147 1},
  • E. Casillas, D. Hoskins
  • Published 1971
  • Biology, Medicine
  • Archives of biochemistry and biophysics
  • Abstract Adenyl cyclase activity was measured in washed ejaculated spermatozoa of the rhesus monkey ( Macaca mulatta ) by monitoring the conversion of [ 14 C]ATP to [ 14 C]cyclic 3′,5′-AMP. Thyroxine and triiodothyronine increase the accumulation of cyclic 3′,5′-AMP; other hormones, including androgens, gonadotropins, prostaglandins, and catecholamines had no effect. Manganese ion, over the range 0.5–20 m m , stimulated adenyl cyclase activity 2- to 50-fold, but in parallel studies inhibited… CONTINUE READING
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