Adenoviruses for treatment of cancer.

  title={Adenoviruses for treatment of cancer.},
  author={Anna Kanerva and Akseli Hemminki},
  journal={Annals of medicine},
  volume={37 1},
Most cases of cancer, when detected at an advanced stage, cannot be cured with conventional therapeutic modalities. Therefore, novel targeted approaches such as gene therapy are needed. Nevertheless, while the safety record of gene therapy for cancer has been excellent with more than a thousand patients treated without mortality related to the therapy, clinical efficacy has so far been limited. Moreover, it has become evident that clinical efficacy is partly determined by efficacy of gene… CONTINUE READING