Adenovirus vector designed for expression of toxic proteins.

  title={Adenovirus vector designed for expression of toxic proteins.},
  author={Dan Edholm and Magnus Molin and Edyta Bajak and G{\"o}ran Akusj{\"a}rvi},
  journal={Journal of virology},
  volume={75 20},
To construct recombinant adenoviruses expressing biologically active proteins may be impossible, or result in a significant reduction in virus yield, if the protein expressed has an inhibitory effect on virus replication or cellular growth. To overcome this problem, we previously designed adenovirus vectors expressing foreign proteins from inducible… CONTINUE READING