Adenovirus type 12-induced rat tumor cells of neuroepithelial origin: persistence and expression of the viral genome.


Four cell lines derived from adenovirus type 12-induced rat brain tumors were studied. The polyploid cells displayed neuroepithelial characteristics and were transplantable into syngeneic rats and nude mice. In tissue culture the cells grew in monolayers and multilayers. A very high saturation density was reached, and the cells plated in agar and were… (More)


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