Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation.

@article{Nishikawa2004AdenovirusmediatedM,
  title={Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation.},
  author={Takashi Nishikawa and Rajagopal Ramesh and Anupama Munshi and Sunil Chada and Raymond E. Meyn},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2004},
  volume={9 6},
  pages={818-28}
}
Melanoma differentiation-associated gene-7 (mda-7), recently classified as interleukin-24 (approved gene symbol IL24), is thought to be a tumor suppressor gene based on the loss of its expression in many different types of cancer. Gene therapy by adenovirus-mediated mda-7 (Ad-mda7) gene transfer has been shown to inhibit the growth of several different… CONTINUE READING