Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels.

@article{Frank2001AdenovirusmediatedEO,
  title={Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels.},
  author={Philippe G Frank and A. J. Donaire Pedraza and David M. Cohen and Michael Phillip Lisanti},
  journal={Biochemistry},
  year={2001},
  volume={40 36},
  pages={10892-900}
}
Caveolae are 50-100 nm plasma membrane invaginations, which function in cell signaling and transcytosis, as well as in regulating cellular cholesterol homeostasis. These subcompartments of the plasma membrane are characterized by the presence of caveolin proteins. Recent studies have indicated that caveolae may be involved in the regulation of cellular cholesterol efflux to HDL, as well as selective uptake mediated by SR-BI. In the present study, we have determined the effect of caveolin-1… CONTINUE READING
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