Adenovirus-mediated ING4/IL-24 double tumor suppressor gene co-transfer enhances antitumor activity in human breast cancer cells.

@article{Zhao2012AdenovirusmediatedID,
  title={Adenovirus-mediated ING4/IL-24 double tumor suppressor gene co-transfer enhances antitumor activity in human breast cancer cells.},
  author={Yaodong Zhao and Zhengyi Li and Weihua Sheng and Jingchen Miao and Jicheng Yang},
  journal={Oncology reports},
  year={2012},
  volume={28 4},
  pages={1315-24}
}
  • Yaodong Zhao, Zhengyi Li, +2 authors Jicheng Yang
  • Published 2012 in Oncology reports
  • DOI:10.3892/or.2012.1930
Cancer gene therapy represents a new and promising therapeutic modality for various types of cancer. Two or more anti-oncogenes carried by a single vector could theoretically improve treatment efficacy, reduce side-effects from vectors, and have a satisfactory clinical application prospect; however, this has seldom been studied in breast cancer. The inhibitor of growth 4 (ING4), as a member of the inhibitor of growth tumor suppressor… CONTINUE READING