Adenovirus-based vaccines against avian-origin H5N1 influenza viruses.

@article{He2015AdenovirusbasedVA,
  title={Adenovirus-based vaccines against avian-origin H5N1 influenza viruses.},
  author={Biao He and Bojian Zheng and Qian Wang and Lanying Du and Shibo Jiang and Lu Lu},
  journal={Microbes and infection},
  year={2015},
  volume={17 2},
  pages={
          135-41
        }
}
Since 1997, human infection with avian H5N1, having about 60% mortality, has posed a threat to public health. In this review, we describe the epidemiology of H5N1 transmission, advantages and disadvantages of different influenza vaccine types, and characteristics of adenovirus, finally summarizing advances in adenovirus-based H5N1 systemic and mucosal vaccines. 
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