Adenovirus DNA synthesis in vitro in an isolated complex.


DNA-protein complexes isolated from adenovirus-infected cells by a modification of the M-band technique were used as an in vitro system for the study of adenovirus DNA replication. The synthesis in vitro was semiconservative, inhibited by N-ethylmaleimide, and stimulated by ATP. Studies on DNA-negative mutants of adenovirus showed that the DNA synthesis in… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.