Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.

@article{Sarti2005AdenoviralTO,
  title={Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.},
  author={Manuela Sarti and Cinzia Sevignani and George A. Calin and Rami Ishaq Aqeilan and Masayoshi Shimizu and Francesca Pentimalli and Maria Cristina Picchio and Andrew K. Godwin and Anne M Rosenberg and Alessandra Drusco and Massimo Negrini and Carlo M. Croce},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2005},
  volume={11 2 Pt 1},
  pages={806-13}
}
PURPOSE The human TESTIN (TES) gene is a putative tumor suppressor gene in the fragile chromosomal region FRA7G at 7q31.1/2 that was reported to be altered in leukemia and lymphoma cell lines. In this report, we investigated the effect of TES gene expression in vivo to evaluate a possible role of TES gene in human cancer. EXPERIMENTAL DESIGN We have analyzed the expression of TES gene in a panel of 25 breast tumors and 17 cell lines of breast, colon, and uterine cancers. Furthermore, to… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 25 references

Mitochondrial intermembrane proteins in cell death.

Biochemical and biophysical research communications • 2003
View 1 Excerpt

Adjuvant pelvic radiotherapy for uterine carcinosarcoma in a high risk population.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology • 2001
View 1 Excerpt

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