Adenoviral strategies for the gene therapy of cancer.

  title={Adenoviral strategies for the gene therapy of cancer.},
  author={Kate Louise Relph and Kevin J. Harrington and Hardev S. Pandha},
  journal={Seminars in oncology},
  volume={32 6},
Despite slow clinical progress, efforts to develop specific nontoxic cancer gene therapies are increasing exponentially. Adenoviral vectors are one of the most popular vehicles for gene transfer currently being used in worldwide clinical trials for cancer. Over the past decade our knowledge of the adenoviral life cycle together with the discovery of novel… CONTINUE READING