Adenoviral infections in hematopoietic stem cell transplantation.

  title={Adenoviral infections in hematopoietic stem cell transplantation.},
  author={Ann M. Leen and Catherine M. Bollard and Gary D Myers and Cliona M Rooney},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  volume={12 3},
Adenoviruses are lytic DNA viruses that are ubiquitous in human communities. In total, 51 different serotypes with varying tissue tropisms have been identified. Adenovirus infections, although frequent, are rarely fatal in immunocompetent individuals who have potent innate and adaptive immunity. But in immunosuppressed individuals, adenoviruses are a significant cause of morbidity and mortality, with limited treatment options. In particular, pediatric recipients of allogeneic hematopoietic stem… CONTINUE READING
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