Adenosine triphosphate-induced sliding of tubules in trypsin-treated flagella of sea-urchin sperm.

@article{Summers1971AdenosineTS,
  title={Adenosine triphosphate-induced sliding of tubules in trypsin-treated flagella of sea-urchin sperm.},
  author={Keith Summers and Ian R. Gibbons},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1971},
  volume={68 12},
  pages={3092-6}
}
Axonemes isolated from the sperm of the sea urchin, Tripneustes gratilla, were briefly digested with trypsin. The digested axonemes retained their typical structure of a cylinder of nine doublet-tubules surrounding a pair of single tubules. The digestion modified the axonemes so that the subsequent addition of 0.1 mM ATP caused them to disintegrate actively into individual tubules and groups. The nucleotide specificity and divalent-cation requirements of this disintegration reaction paralleled… CONTINUE READING