Adenosine-sensitive ventricular tachycardia: evidence suggesting cyclic AMP-mediated triggered activity.

@article{Lerman1986AdenosinesensitiveVT,
  title={Adenosine-sensitive ventricular tachycardia: evidence suggesting cyclic AMP-mediated triggered activity.},
  author={Bruce B. Lerman and Luiz Belardinelli and G. Alexander West and Robert M. Berne and John P Dimarco},
  journal={Circulation},
  year={1986},
  volume={74 2},
  pages={270-80}
}
Catecholamine-induced triggered activity is thought to be caused by intracellular calcium overload mediated by elevation of intracellular cyclic AMP (cAMP). Although shown to occur in isolated preparations, evidence supporting its clinical existence has been lacking. Electrophysiologic studies were performed in four patients with structurally normal hearts who had exertionally related sustained ventricular tachycardia (VT). Programmed stimulation reproducibly initiated and terminated VT in all… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 101 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

A comparison between muscarinic receptor occupancy , adenylate cyclase inhibition , and inotropic response in human heart

  • M Delhaye, JM DeSmet, +6 authors J Christophe
  • Arch Pharmacol
  • 1984

Similar Papers

Loading similar papers…