Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ.

@article{Porter1995AdenosineRM,
  title={Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ.},
  author={James T. Porter and K. D. Mccarthy},
  journal={Journal of neurochemistry},
  year={1995},
  volume={65 4},
  pages={
          1515-23
        }
}
Cultured astroglia express both adenosine and ATP purinergic receptors that are coupled to increases in intracellular calcium concentration ([Ca2+]i). Currently, there is little evidence that such purinergic receptors exist on astrocytes in vivo. To address this issue, calcium-sensitive fluorescent dyes were used in conjunction with confocal microscopy and immunocytochemistry to examine the responsiveness of astrocytes in acutely isolated hippocampal slices to purinergic neuroligands. Both ATP… CONTINUE READING
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