Adenosine receptors as therapeutic targets

  title={Adenosine receptors as therapeutic targets},
  author={Kenneth A. Jacobson and Z L Gao},
  journal={Nature Reviews Drug Discovery},
Adenosine receptors are major targets of caffeine, the most commonly consumed drug in the world. There is growing evidence that they could also be promising therapeutic targets in a wide range of conditions, including cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. After more than three decades of medicinal chemistry research, a considerable number of selective agonists and antagonists of adenosine receptors have been discovered, and some… CONTINUE READING
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