Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin.

@article{Chern1988AdenosineRA,
  title={Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin.},
  author={Y J Chern and Kyung Tack Kim and Linda L. Slakey and Edward W. Westhead},
  journal={Journal of neurochemistry},
  year={1988},
  volume={50 5},
  pages={
          1484-93
        }
}
Cells of the adrenal medulla release not only catecholamines but also high concentrations of neuropeptides and nucleotides. Chromaffin cells, like many neuronal cells, have a diversity of receptors: adrenergic receptors, peptide receptors, histamine receptors, and dopamine receptors. We recently reported that these cells have nucleotide receptors that can mediate inhibition of the secretory response. The present studies show that adenosine, in the presence of enabling concentrations of… CONTINUE READING
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