Adenosine receptor subtypes in the heart: therapeutic opportunities and challenges.

@article{Auchampach1999AdenosineRS,
  title={Adenosine receptor subtypes in the heart: therapeutic opportunities and challenges.},
  author={John A. Auchampach and Roberto Bolli},
  journal={The American journal of physiology},
  year={1999},
  volume={276 3 Pt 2},
  pages={H1113-6}
}
FOUR SUBTYPES OF ADENOSINE RECEPTORS (A1, A2A, A2B, and A3 receptors) are known to exist (26). Traditionally, the A1-adenosine receptor has been thought to be the only subtype expressed in ventricular cardiomyocytes. By inhibiting adenylyl cyclase, the A1 receptor attenuates the positive inotropic effect of b-adrenergic receptor stimulation (or other… CONTINUE READING