Adenosine modulates oesophageal sensorimotor function in humans

  title={Adenosine modulates oesophageal sensorimotor function in humans},
  author={Jose Mar{\'i}a Remes-Troche and Premjit S Chahal and Ranjit S. Mudipalli and S S Rao},
  pages={1049 - 1055}
Background and aims: Adenosine mediates somatic and visceral pain, but its effects on gut visceral nociception are unknown. The aim of the present study was to test the hypothesis that adenosine alters oesophageal sensorimotor function. Methods: In a double-blind, randomised, placebo-controlled study, 14 healthy volunteers (M/F = 4/10) received either intravenous adenosine 100 μg/kg/min or placebo infusion. Prior to and during infusion, all subjects underwent stepwise graded oesophageal balloon… 

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