Adenosine kinase gene expression in human colorectal cancer.

  title={Adenosine kinase gene expression in human colorectal cancer.},
  author={Stefania Giglioni and Roberto Leoncini and Emilia Aceto and A Chessa and Serenella Civitelli and Andrea Bernini and Gabriello Tanzini and Fabio Carraro and Angela Pucci and Daniela Vannoni},
  journal={Nucleosides, nucleotides & nucleic acids},
  volume={27 6},
Real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to evaluate gene expression of adenosine kinase, a key enzyme in adenosine metabolism, in human intestinal biopsy specimens of 10 colorectal cancer patients. Quantitative mRNA expression levels were normalized against the reference gene beta-actin. The results showed that adenosine… CONTINUE READING