Adenosine kinase and ribokinase – the RK family of proteins

@article{Park2008AdenosineKA,
  title={Adenosine kinase and ribokinase – the RK family of proteins},
  author={J. Park and R. Gupta},
  journal={Cellular and Molecular Life Sciences},
  year={2008},
  volume={65},
  pages={2875-2896}
}
  • J. Park, R. Gupta
  • Published 2008
  • Biology, Medicine
  • Cellular and Molecular Life Sciences
  • Abstract.Ribokinase (RK) and adenosine kinase (AK) catalyze the phosphorylation of ribose and adenosine to ribose-5-phosphate and AMP, respectively. Belonging to the RK family of proteins, these enzymes share a number of unique structural and functional elements. Extensive work has been carried out on many aspects of these enzymes in recent years, and we summarize the wealth of information currently available on them. The topics covered include descriptions of the primary and three-dimensional… CONTINUE READING
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    References

    SHOWING 1-10 OF 169 REFERENCES
    The Effect of Inorganic Phosphate on the Activity of Bacterial Ribokinase
    • 18
    Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases.
    • 125
    • PDF
    Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives
    • 12
    Hypothesis: structures, evolution, and ancestor of glucose kinases in the hexokinase family.
    • 86
    Purification, characterization, and crystallization of Escherichia coli ribokinase
    • 31
    Induced fit on sugar binding activates ribokinase.
    • 70
    Deoxyribokinase from Salmonella typhimurium. Purification and properties.
    • 15
    Structure of human adenosine kinase at 1.5 A resolution.
    • 167
    • PDF