Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells.

Abstract

Adenosine is produced during cellular hypoxia and apoptosis, resulting in elevated tissue levels at sites of injury. Adenosine is also known to regulate a number of cellular responses to injury, but its role in hepatic stellate cell (HSC) biology and liver fibrosis is poorly understood. We tested the effect of adenosine on the cytosolic Ca2+ concentration… (More)

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@article{Hashmi2007AdenosineIC, title={Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells.}, author={Ardeshir Z Hashmi and Wyel Hakim and Emma A Kruglov and Azuma Watanabe and William Watkins and Jonathan A. Dranoff and Wajahat Zafar Mehal}, journal={American journal of physiology. Gastrointestinal and liver physiology}, year={2007}, volume={292 1}, pages={G395-401} }