Adenosine-induced apoptosis in EL-4 thymoma cells is caspase-independent and mediated through a non-classical adenosine receptor.

Abstract

Cell death caused by the accumulation of extracellular adenosine is believed to contribute to the profound loss of T lymphocytes in patients with severe combined immunodeficiency disease due to adenosine deaminase deficiency. Although adenosine is known to trigger apoptosis in thymocytes and peripheral T cells, the molecular basis of this effect is not… (More)

Topics

Cite this paper

@article{ElDarahali2005AdenosineinducedAI, title={Adenosine-induced apoptosis in EL-4 thymoma cells is caspase-independent and mediated through a non-classical adenosine receptor.}, author={Asile El-Darahali and Helen Fawcett and Jamie S. Mader and David Conrad and David W. Hoskin}, journal={Experimental and molecular pathology}, year={2005}, volume={79 3}, pages={249-58} }