Adenosine dephosphorylates myosin light chain in primary cultures of vascular smooth muscle cells from normotensive and spontaneously hypertensive rats.


OBJECTIVE The aim was to determine whether vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) respond differently to adenosine than those from normotensive Wistar-Kyoto (WKY) rats. DESIGN Confluent primary cultures of VSMC derived from SHR and WKY aorta and mesenteric arteries and cerebral arteries were used. The effect of… (More)