Adenosine deaminase activity in patients with Crohn's disease: distinction between active and nonactive disease.

@article{Maor2011AdenosineDA,
  title={Adenosine deaminase activity in patients with Crohn's disease: distinction between active and nonactive disease.},
  author={Irit Maor and Tova Rainis and Amos Lanir and Alexandra Lavy},
  journal={European journal of gastroenterology & hepatology},
  year={2011},
  volume={23 7},
  pages={598-602}
}
BACKGROUND Crohn's disease (CD) is a common chronic inflammatory bowel disease. During the disease a cascade of immunologic events occur including mucosal influx of inflammatory cells like neutrophils. Adenosine deaminase (ADA) is important in inflammatory responses and serves as a marker of activated leukocytes. MATERIALS AND METHODS In this study, we investigated the activity of total ADA (tADA) and its isoenzymes, ADA1 and ADA2, in serum and neutrophils derived from 20 active patients with… CONTINUE READING

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