Adenosine antagonists combined with 4-aminopyridine cause partial recovery of synaptic transmission in low Ca media

@article{Schubert1988AdenosineAC,
  title={Adenosine antagonists combined with 4-aminopyridine cause partial recovery of synaptic transmission in low Ca media},
  author={Peter Schubert and Uwe F Heinemann},
  journal={Experimental Brain Research},
  year={1988},
  volume={70},
  pages={539-549}
}
Orthodromically and antidromically evoked field potentials, as well as changes in the extracellular calcium concentration [Ca2+]0 were measured with ion selective/reference electrodes in area CA1 of rat hippocampal slices. Synaptic transmission was blocked by a low calcium, high magnesium medium. After cutting through the alveus, stratum pyramidale (Spyr) and part of stratum radiatum (Srad), repetitive electrical stimulation of Schaffer collaterals and commissural fibers elicited decreases of… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 37 references

The action

  • S Francescetti, B Hamon, U Heinemann
  • 1986

The action of valporate on spontaneous epileptiform activity in the absence of synaptic transmission and on evoked changes in [ Ca 2 + ] o and [ K + ] o in the hippocampal slice

  • S Francescetti, B Hamon, U Heinemann
  • Brain Res
  • 1986

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