Adenosine antagonists as potential therapeutic agents

@article{Williams1988AdenosineAA,
  title={Adenosine antagonists as potential therapeutic agents},
  author={M. Williams and M. Jarvis},
  journal={Pharmacology Biochemistry and Behavior},
  year={1988},
  volume={29},
  pages={433-441}
}
  • M. Williams, M. Jarvis
  • Published 1988
  • Psychology, Medicine
  • Pharmacology Biochemistry and Behavior
  • The methylxanthine caffeine has been identified in more than 60 plant species and has been in human use for its various therapeutic actions for many hundreds of years and perhaps, with the exception of aspirin and related compounds, is the most widely consumed drug today. Pharmacologically, the xanthines are prototypic inhibitors of the enzyme, cyclic nucleotide phosphodiesterase, are calcium mobilizers and have been reported to inhibit the enzymes, monoamine oxidase and cyclooxygenase as well… CONTINUE READING
    50 Citations
    Adenosine: The prototypic neuromodulator
    • M. Williams
    • Biology, Medicine
    • Neurochemistry International
    • 1989
    • 121

    References

    SHOWING 1-10 OF 100 REFERENCES
    Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists.
    • R. Bruns, J. Daly, S. Snyder
    • Chemistry, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1983
    • 132
    • PDF
    Adenosine receptors and behavioral actions of methylxanthines.
    • 655
    • PDF
    Biochemical characterization of the triazoloquinazoline, CGS 15943, a novel, non-xanthine adenosine antagonist.
    • 108
    Characterization of adenosine receptors in isolated cerebral arteries of cat
    • 116
    Purine receptors in mammalian tissues: pharmacology and functional significance.
    • M. Williams
    • Biology, Medicine
    • Annual review of pharmacology and toxicology
    • 1987
    • 286
    Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists.
    • 101