Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells

@article{Rathbone1992AdenosineAI,
  title={Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells},
  author={Michel Piers Rathbone and Pamela J. Middlemiss and Ji-Eun Kim and John W. Gysbers and David W. Hughes},
  journal={Neuroscience Research},
  year={1992},
  volume={13},
  pages={1-17}
}
Aqueous extracts of the brains of 18-day-old white Leghorn chicken embryos contain several substances that stimulate proliferation of primary cultures of chick brain astrocytes. Most of the mitogens are peptides. Purification of one mitogenic fraction was obtained by centrifugation, passage through Amicon Diaflo membranes of nominal molecular weight cutoffs 30, 1 and 0.5 kDa, ion exchange chromatography and reverse phase high performance liquid chromatography (HPLC) using a Deltapak C18 column… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 45 CITATIONS

Purinergic signalling and cancer

  • Purinergic Signalling
  • 2013
VIEW 1 EXCERPT
CITES BACKGROUND