Adenosine activates afferent fibers in the forearm, producing sympathetic stimulation in humans.

@article{Costa1993AdenosineAA,
  title={Adenosine activates afferent fibers in the forearm, producing sympathetic stimulation in humans.},
  author={Fernando Costa and Italo Biaggioni},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1993},
  volume={267 3},
  pages={1369-74}
}
Whereas adenosine is generally considered an inhibitory neuromodulator, there is evidence that adenosine may excite a variety of afferent fibers thereby evoking sympathetic activation. To determine whether adenosine also excites afferent fibers located in the forearm, adenosine was administered into the left branchial artery at doses without systemic effects while sympathetic nerve activity was monitored through a recording electrode placed in the right peroneal nerve in the lower limb. The i.a… CONTINUE READING

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