Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury.

Abstract

BACKGROUND Severe ischemia-reperfusion (IR) injury leads to primary graft dysfunction after lung transplantation. Adenosine receptors modulate inflammation after IR, and the adenosine A3 receptor (A3R) is expressed in lung tissue and inflammatory cells. This study tests the hypothesis that A3R agonism attenuates lung IR injury by a neutrophil-dependent… (More)
DOI: 10.1016/j.athoracsur.2013.01.059

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@article{Mulloy2013AdenosineAR, title={Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury.}, author={Daniel P. Mulloy and Ashish K Sharma and L Garc{\'i}a- Fern{\'a}ndez and Yunge Zhao and Christine Lau and Irving L. Kron and Victor E Laubach}, journal={The Annals of thoracic surgery}, year={2013}, volume={95 5}, pages={1762-7} }