Adenosine A2a receptors increase arterial endothelial cell nitric oxide.

@article{Li1998AdenosineAR,
  title={Adenosine A2a receptors increase arterial endothelial cell nitric oxide.},
  author={J. Li and R. Fenton and H. B. Wheeler and C. Powell and B. Peyton and B. Cutler and J. G. Dobson},
  journal={The Journal of surgical research},
  year={1998},
  volume={80 2},
  pages={
          357-64
        }
}
BACKGROUND Adenosine is a potent vasodilator of vascular smooth muscle. Endothelium-derived nitric oxide (NO) elicits vasodilation. We have previously reported that adenosine stimulates the production of NO from porcine carotid arterial endothelial cells (PCAEC) via a receptor-mediated mechanism. This study was to determine whether adenosine also enhances NO production from human arterial endothelium and to define the involvement of adenosine A1 and A2 receptors. MATERIALS AND METHODS Human… Expand
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