Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons.

Abstract

The function of adenosine A(2A) receptors, localized at the enkephalin-containing GABAergic medium spiny neurons of the striatum, has been discussed controversially. Here we show that, in the absence of external Mg(2+), the adenosine A(2A) receptor agonist CGS 21680 postsynaptically depressed the NMDA, but not the non-NMDA (AMPA/kainate) receptor-mediated… (More)

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@article{Wirkner2004AdenosineAR, title={Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons.}, author={Kerstin Wirkner and Zolt{\'a}n Gerevich and Thomas Krause and Albrecht Guenther and L{\'a}szl{\'o} K{\"o}les and Dietmar Schneider and Wolfgang N{\"o}renberg and P{\'e}ter Ill{\'e}s}, journal={Neuropharmacology}, year={2004}, volume={46 7}, pages={994-1007} }