Adenosine A2A receptor antagonists as novel anti-Parkinsonian agents: a review of structure-activity relationships.


The adenosine A2A receptor (AA2AR) has emerged as an attractive target for the treatment of Parkinson's disease. Evidence suggests that antagonists of the AA2AR may be neuroprotective and may help to alleviate the symptoms of Parkinson's disease. During last decade, many efforts have been accomplished searching potent and selective AA2AR antagonists. In… (More)


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