Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.

@article{Canals2003AdenosineAD,
  title={Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.},
  author={Meritxell Canals and Daniel Marcellino and Francesca Fanelli and Francisco Ciruela and Piero de Benedetti and Steven R. Goldberg and Kim A Neve and Kjell Fuxe and Luigi Francesco Agnati and Amina S Woods and Sergi Ferr{\'e} and Carme Llu{\'i}s and Michel Bouvier and Rafael Franco},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 47},
  pages={46741-9}
}
There is evidence for strong functional antagonistic interactions between adenosine A2A receptors (A2ARs) and dopamine D2 receptors (D2Rs). Although a close physical interaction between both receptors has recently been shown using co-immunoprecipitation and co-localization assays, the existence of a A2AR-D2R protein-protein interaction still had to be demonstrated in intact living cells. In the present work, fluorescence resonance energy transfer (FRET) and bioluminescence resonance energy… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 140 extracted citations

Similar Papers

Loading similar papers…