Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins.

@article{TrendellSmith1999AdenoidCC,
  title={Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins.},
  author={Nigel Jeremy Trendell-Smith and David Peston and Sami Shousha},
  journal={Histopathology},
  year={1999},
  volume={35 3},
  pages={241-8}
}
AIM Adenoid cystic carcinoma (ACC) of the breast is an uncommon well-differentiated tumour with good prognosis, and sometimes difficult to distinguish from in-situ and invasive cribriform carcinoma (ICC) which are relatively more common. Recently, we encountered a case of ACC that proved to be totally oestrogen receptor (ER) negative by immunohistochemistry. We investigated the possibility that this may be a consistent feature that can help in differentiating ACC from ICC which are usually ER… CONTINUE READING