Adenoid cystic/basal cell carcinoma of the prostate strongly expresses HER-2/neu.

@article{Iczkowski2006AdenoidCC,
  title={Adenoid cystic/basal cell carcinoma of the prostate strongly expresses HER-2/neu.},
  author={Kenneth A. Iczkowski and Rodolfo Montironi},
  journal={Journal of clinical pathology},
  year={2006},
  volume={59 12},
  pages={
          1327-30
        }
}
Adenoid cystic/basal cell carcinoma (ACBCC) is a rare neoplasm in the prostate. Definitive treatment is warranted, as among 19 patients previously reported by us, 5 had extraprostatic extension and 4 were metastatic. The HER-2/neu (c-erbB-2) gene has been reportedly overexpressed in adenoid cystic carcinomas in other organs, but its status in prostatic ACBCC was uncertain. Immunohistochemical staining and in situ hybridisation were carried out in 13 patients with ACBCC (11 from transurethral… CONTINUE READING