Adenocarcinoma Cells via Cyclic GMP Mouse and Induces Apoptosis in Human Colon Min / + Apc Uroguanylin Treatment Suppresses Polyp Formation in the Updated


The enteric peptides, guanylin and uroguanylin, are local regulators of intestinal secretion by activation of receptor-guanylate cyclase (R-GC) signaling molecules that produce cyclic GMP (cGMP) and stimulate the cystic fibrosis transmembrane conductance regulator-dependent secretion of Cl and HCO3 . Our experiments demonstrate that mRNA transcripts for… (More)

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