Adeno-Associated Virus

  title={Adeno-Associated Virus},
  author={Richard O. Snyder and Philippe Moullier and Jude Samulski},
  booktitle={Methods in Molecular Biology},
Adeno-associated virus (AAV) was fi rst discovered as a contaminant of adenovirus stocks in the 1960s. The development of recombinant AAV vectors (rAAV) was facilitated by early studies that generated infectious molecular clones, determined the sequence of the genome, and defi ned the genetic elements of the virus. The refi nement of methods and protocols for the production and application of rAAV vectors has come from years of studies that explored the basic biology of this virus and its… CONTINUE READING

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