Addressing the challenges of cardiorenal syndrome.

  title={Addressing the challenges of cardiorenal syndrome.},
  author={Carrie Anna Geisberg and Javed Butler},
  journal={Cleveland Clinic journal of medicine},
  volume={73 5},
In heart failure, as the heart gets worse, often so do the kidneys, complicating the treatment of heart failure and worsening the prognosis. This article addresses challenges in the use of diuretics, angiotensin-converting enzyme (ACE) inhibitors, and other therapies in the cardiorenal syndrome, as well as novel therapies that hold promise, such as arginine vasopressin antagonists, adenosine A1 receptor antagonists, and ultrafiltration.