Additive myocardial depressant effects of cocaine and ethanol.

  title={Additive myocardial depressant effects of cocaine and ethanol.},
  author={R T Uszenski and Richard A. Gillis and Gary L. Schaer and A R Analouei and Fritz Kuhn},
  journal={American heart journal},
  volume={124 5},
Although significant morbidity and mortality have been associated with the combined use of cocaine and ethanol, the cardiovascular effects of this combination are unknown. In this study, the effect of ethanol on cocaine-induced cardiovascular alterations was examined in two groups (n = 8 each) of dogs, which were randomized to receive either ethanol (1.68 gm/kg intravenously) or saline solution and cocaine (2 mg/kg intravenously). Ethanol had no effect on heart rate, mean arterial pressure, or… CONTINUE READING

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