Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis.

Abstract

We studied the effects of combination treatment with an anti-inflammatory agent, interferon (IFN)-beta, and a putative neuroprotective agent, an estrogen receptor (ER)-beta ligand, during EAE. Combination treatment significantly attenuated EAE disease severity, preserved axonal densities in spinal cord, and reduced CNS inflammation. Combining ERbeta… (More)
DOI: 10.1016/j.jneuroim.2009.11.018

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Cite this paper

@article{Du2010AdditiveEO, title={Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis.}, author={Sienmi Du and Francisco E Hernandez Sandoval and Pauline N Trinh and Rhonda R. Voskuhl}, journal={Journal of neuroimmunology}, year={2010}, volume={219 1-2}, pages={64-74} }