Additive effects in the palladium-catalyzed carboiodination of chiral N-allyl carboxamides.

@article{Petrone2014AdditiveEI,
  title={Additive effects in the palladium-catalyzed carboiodination of chiral N-allyl carboxamides.},
  author={David A Petrone and Hyung Yoon and Harald Weinstabl and Mark Lautens},
  journal={Angewandte Chemie},
  year={2014},
  volume={53 30},
  pages={
          7908-12
        }
}
The use of Pd catalysis as a means to synthesize organic halides has recently received increased attention. Among the reported methods is the Pd-catalyzed carboiodination, which uses extremely bulky ligands to facilitate carbon-halogen reductive elimination from Pd(II) as the key catalytic step. When approaching substrates exhibiting low stereoselectivity, catalyst troubleshooting becomes difficult as there are few ligands known to promote the key reductive elimination. Herein, we present our… Expand
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