Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin‐treated glaucoma patients

@inproceedings{Aihara2017AdditiveEA,
  title={Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin‐treated glaucoma patients},
  author={Makoto Aihara and Misato Adachi and Hiroshi Matsuo and Tetsuya Togano and Takeo Fukuchi and Noriyuki Sasaki and Yohei Chikaraishi and Jun Ueda and Yuta Sakaue and Akiko Ohta and Motohiro Shirakashi and Kiyoshi Yaoeda and Takayuki Tanaka and Tetsunari Oyama and Shigeru Hoshiai and Shunei Gen and Shuuko Fujitani and Arata Sekine and Masahiro Fujita and Yukihiro Matsumoto and Hirotaka Suzumura and Takuji Kato and Sakae Matsuzaki and Setsuko Hashida and Shunichi Sato and Isao Sato and Tomoyuki Muramatsu and Akira L. Ando and Masamitsu Takeuchi and Shingo Onoe and Shinichi Manabe and Yumi Oda and Kumi Horikawa and Kaori Kifuku and Ken Hayashi and Mineo Ozaki and Saya Ishii and Akiko Matsuyama and Takashi Komizo and Kazunori Miyata and Shinichiro Otani and Fumie Kagaya and Junko Hanaya and Kazuhiko Unoki and Shigeko Unoki and Takehiro Yamashita and Toyomi Yamashita},
  booktitle={Acta ophthalmologica},
  year={2017}
}
PURPOSE To compare the additive effects and safety of 1% brinzolamide/0.5% timolol fixed combination (BTFC) versus the low-dose regimen of 1% dorzolamide/0.5% timolol fixed combination (DTFC) in patients with open-angle glaucoma and ocular hypertension (OAG/OH) following treatment with prostaglandin analogues (PGAs). METHODS A prospective, randomized, double-masked, multicentre, parallel-group and active-controlled study included 201 Japanese OAG/OH patients who had been treated with PGA… CONTINUE READING

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