Additive effect of pneumococcal vaccine and influenza vaccine on acute exacerbation in patients with chronic lung disease.

@article{Furumoto2008AdditiveEO,
  title={Additive effect of pneumococcal vaccine and influenza vaccine on acute exacerbation in patients with chronic lung disease.},
  author={Akitsugu Furumoto and Yasushi Ohkusa and Meng Chen and Kenji Patents Divisio Kawakami and Hironori Masaki and Yoshiko Sueyasu and Tomoaki Iwanaga and Hisamichi Aizawa and Tsuyoshi Nagatake and Kazunori Oishi},
  journal={Vaccine},
  year={2008},
  volume={26 33},
  pages={
          4284-9
        }
}
To determine the clinical efficacy of combined vaccination with 23-valent pneumococcal vaccine (PV) and influenza vaccine (IV) against pneumonia and acute exacerbation of chronic lung diseases (CLD), we conducted an open-label, randomized, controlled study among 167 adults with CLD over a 2-year period. Subjects were randomly assigned to a PV+IV group (n=87) or an IV group (n=80). The number of patients with CLD experiencing infectious acute exacerbation (P=0.022), but not pneumonia (P=0.284… CONTINUE READING
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