Additive contributions of childhood adversity and recent stressors to inflammation at midlife: Findings from the MIDUS study.

@article{Hostinar2015AdditiveCO,
  title={Additive contributions of childhood adversity and recent stressors to inflammation at midlife: Findings from the MIDUS study.},
  author={Camelia Elena Hostinar and Margie Lachman and Daniel K Mroczek and Teresa Seeman and Gregory E Miller},
  journal={Developmental psychology},
  year={2015},
  volume={51 11},
  pages={1630-44}
}
We examined the joint contributions of self-reported adverse childhood experiences (ACEs) and recent life events (RLEs) to inflammation at midlife, by testing 3 competing theoretical models: stress generation, stress accumulation, and early life stress sensitization. We aimed to identify potential mediators between adversity and inflammation. Participants were 1,180 middle-aged and older adults from the Midlife in the United States (MIDUS) Biomarker Project (M age = 57.3 years, SD = 11.5; 56… CONTINUE READING